The Rab2A Polyclonal Antibody is a valuable tool for researchers studying Rab2A, a small GTPase protein involved in intracellular transport and vesicle trafficking processes. This antibody, generated in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By binding specifically to Rab2A protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for investigations in cell biology and molecular biology.Rab2A is known to regulate vesicular transport between the endoplasmic reticulum and Golgi apparatus, as well as play a role in autophagy and mitochondrial dynamics.
Dysfunction of Rab2A has been associated with various diseases, including neurodegenerative disorders and cancer, making it a compelling target for research aimed at understanding these pathologies. By studying the function of Rab2A, researchers can gain insights into cellular processes and potentially identify new therapeutic targets for disease intervention.
Product Name:
RAB2A Polyclonal Antibody
SKU:
CAB21582
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human RAB2A (NP_002856.1).
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB2A Rabbit pAb (CAB21582) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
