The Rab2A Polyclonal Antibody (CAB11634) is a valuable tool for researchers studying Rab2A, a small GTPase protein involved in regulating intracellular membrane trafficking. This antibody, generated in rabbits, exhibits high specificity and reactivity towards Rab2A in human samples, and has been validated for use in Western blot applications.Rab2A plays a key role in coordinating vesicle transport between the endoplasmic reticulum and the Golgi apparatus, as well as in autophagy and organelle dynamics. Dysregulation of Rab2A has been implicated in various diseases, including neurodegenerative disorders and cancer.
Therefore, studying Rab2A using the Rab2A Polyclonal Antibody can provide insights into its function and potential therapeutic targets.Researchers in cell biology, neurobiology, cancer research, and related fields can benefit from the Rab2A Polyclonal Antibody for investigating the intracellular trafficking pathways and cellular processes involving Rab2A. Its specificity and reactivity make it a reliable tool for the detection and analysis of Rab2A in various cell types, aiding in the understanding of its role in health and disease.
Product Name:
RAB2A Rabbit Polyclonal Antibody
SKU:
CAB11634
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human RAB2A (NP_002856.1).
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RAB2A Rabbit pAb (CAB11634) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
