The Rab28 Polyclonal Antibody (CAB17368) is a valuable tool for researchers studying Rab28, a member of the Rab GTPase family that plays a crucial role in regulating intracellular transport and membrane trafficking processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Rab28 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in cell biology, molecular biology, and related fields.
Rab28 is involved in the transport of proteins and vesicles within cells, impacting diverse cellular processes such as autophagy, secretion, and organelle dynamics. Dysregulation of Rab28 function has been implicated in various diseases, including ciliopathies, cancer, and neurodegenerative disorders. By studying the role of Rab28 using this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets for intervention.
Product Name:
RAB28 Rabbit Polyclonal Antibody
SKU:
CAB17368
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-170 of human RAB28 (NP_001017979.1).
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X.
Purification Method:
Affinity purification
Gene ID:
9364
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using RAB28 Rabbit pAb (CAB17368) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.