The Rab27b Polyclonal Antibody (CAB10389), I have crafted the following product description:The Rab27b Polyclonal Antibody (CAB10389) is specifically designed for research involving Rab27b, a protein belonging to the Rab family of small GTPases that plays a crucial role in intracellular vesicle trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.Rab27b is known to be involved in regulating the transportation and secretion of vesicles containing important signaling molecules, making it a key player in processes such as exosome release, neurotransmitter secretion, and immune cell function.
By binding to Rab27b, this antibody enables the precise detection and analysis of this protein in a variety of cell types, making it an invaluable tool for studies in cell biology, immunology, and neuroscience.Understanding the function of Rab27b is essential for elucidating its role in cellular processes and diseases such as cancer, neurological disorders, and immune-related conditions. By targeting Rab27b and investigating its signaling pathways, researchers can gain insights that may lead to the development of novel therapeutic strategies aimed at modulating vesicle trafficking and secretion dynamics in health and disease.
Product Name:
RAB27B Rabbit Polyclonal Antibody
SKU:
CAB10389
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human RAB27B (NP_004154.2).
Enables guanyl ribonucleotide binding activity; myosin V binding activity; and protein domain specific binding activity. Involved in multivesicular body sorting pathway and positive regulation of exocytosis. Located in Golgi stack and cytoplasmic vesicle.
Purification Method:
Affinity purification
Gene ID:
5874
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using RAB27B Rabbit pAb (CAB10389) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 25s.
