The Rab23 Polyclonal Antibody (CAB7979) is a research tool designed for investigating the Rab23 protein, a key regulator of intracellular trafficking and cellular signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications. By binding specifically to Rab23, this antibody enables precise detection and analysis of the protein in various cell types, making it an ideal choice for studies in cell biology and signal transduction research.Rab23 is a critical component of the Rab family of small GTPases, playing a crucial role in the regulation of vesicle trafficking and intracellular membrane dynamics.
Dysregulation of Rab23 has been linked to various diseases, including cancer and developmental disorders. Studying the function and regulation of Rab23 with the use of this antibody can provide valuable insights into its role in cellular processes and disease pathogenesis.Overall, the Rab23 Polyclonal Antibody (CAB7979) serves as a valuable tool for researchers seeking to explore the functions and mechanisms of action of Rab23 in cell biology and disease, offering reliable and specific detection for accurate experimental results.
Product Name:
RAB23 Rabbit Polyclonal Antibody
SKU:
CAB7979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human RAB23 (NP_057361.3).
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB23 antibody (CAB7979) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
