RAB21 Rabbit Polyclonal Antibody (CAB12095)
- SKU:
- CAB12095
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | RAB21 Rabbit Polyclonal Antibody |
SKU: | CAB12095 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human RAB21 (NP_055814.1). |
Sequence: | MAAA GGGG GGAA AAGR AYSF KVVL LGEG CVGK TSLV LRYC ENKF NDKH ITTL QASF LTKK LNIG GKRV NLAI WDTA GQER FHAL GPIY YRDS NGAI LVYD ITDE DSFQ KVKN WVKE LRKM LGNE ICLC IVGN KIDL EKER HVSI QEAE SYAE SVGA KHYH TSAK QNKG IEEL FLDL CKRM IETA QVDE RAKG NGSS QPGT ARRG VQII DDEP QAQT SGGG CCSS G |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | RAB21 |
Positive Sample: | HT-29,293T,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cleavage furrow, Cytoplasmic vesicle membrane, Early endosome membrane, Endoplasmic reticulum membrane, Golgi apparatus, Golgi apparatus membrane, Lipid-anchor, trans-Golgi network. |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues.
Purification Method: | Affinity purification |
Gene ID: | 23011 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |