The Rab21 Polyclonal Antibody (CAB12095) is a valuable tool for researchers studying Rab21, a small GTPase involved in regulating membrane trafficking and vesicle formation. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and shows high reactivity with human samples.Rab21 plays a crucial role in various cellular processes, including endocytosis, exocytosis, and recycling of cell surface receptors. Its dysregulation has been implicated in diseases such as cancer, neurodegenerative disorders, and infectious diseases.
By targeting Rab21 with this antibody, researchers can explore its functions in different cell types and gain insight into its role in health and disease.With its high specificity and sensitivity, the Rab21 Polyclonal Antibody is a valuable tool for investigations into membrane trafficking pathways, intracellular signaling events, and potential therapeutic targets. Researchers in cell biology, molecular biology, and drug discovery will find this antibody essential for their studies.
Product Name:
RAB21 Rabbit Polyclonal Antibody
SKU:
CAB12095
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human RAB21 (NP_055814.1).
This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues.
Purification Method:
Affinity purification
Gene ID:
23011
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB21 Rabbit pAb (CAB12095) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
