The Rab1B Polyclonal Antibody (CAB7514) is a valuable tool for researchers studying the Rab1B protein, a key regulator of vesicle trafficking and protein transport within cells. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting Rab1B in human samples, making it an ideal choice for Western blot applications.Rab1B is a member of the Ras family of small GTPases and is involved in the transport of proteins between the endoplasmic reticulum (ER) and the Golgi apparatus. Dysregulation of Rab1B has been linked to various diseases including cancer, neurodegenerative disorders, and infectious diseases.
By targeting Rab1B with this antibody, researchers can gain valuable insights into the role of this protein in cellular processes and disease pathogenesis.The Rab1B Polyclonal Antibody is a valuable tool for investigating the function and regulation of Rab1B in various cellular contexts. Its high specificity and sensitivity allow for precise detection and analysis of Rab1B levels, making it an essential component of research in cell biology, molecular biology, and disease mechanisms.
Product Name:
RAB1B Rabbit Polyclonal Antibody
SKU:
CAB7514
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 7-201 of human RAB1B (NP_112243.1).
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).
Purification Method:
Affinity purification
Gene ID:
81876
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and RAB1B knockout (KO) HeLa cells using [KO Validated] RAB1B Rabbit pAb RAB1B Rabbit pAb (CAB7514) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
