The Rab1B Polyclonal Antibody (AB10009) is a valuable tool for research involving Rab1B, a small GTPase involved in intracellular membrane trafficking and vesicle transport. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By targeting the Rab1B protein, this antibody enables the detection and analysis of Rab1B in various cell types, facilitating studies in cell biology, protein trafficking, and signal transduction pathways.Rab1B is a key player in regulating the transport of proteins between the endoplasmic reticulum and the Golgi apparatus, as well as in maintaining organelle integrity and function.
Its role in membrane trafficking processes underscores its importance in cellular homeostasis and disease progression, particularly in conditions such as neurodegenerative disorders, viral infections, and cancer. Investigating the functions and interactions of Rab1B is essential for advancing our understanding of cellular trafficking mechanisms and developing targeted therapies for related diseases.
Product Name:
RAB1B Polyclonal Antibody
SKU:
CAB21669
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 7-201 of human RAB1B (NP_112243.1).
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).
Purification Method:
Affinity purification
Gene ID:
81876
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB1B Rabbit pAb (CAB21669) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
