The Rab1A Polyclonal Antibody (CAB17364) is specifically designed for research involving Rab1A, a small GTPase protein that plays a key role in regulating intracellular membrane trafficking. This antibody, produced in rabbits, is highly sensitive and reactive with human samples, making it an ideal tool for studying Rab1A in various cellular processes.Rab1A is involved in the transport of proteins between different cellular compartments, such as the endoplasmic reticulum and the Golgi apparatus. Dysregulation of Rab1A has been implicated in various diseases, including neurodegenerative disorders and cancer.
By targeting Rab1A with this antibody, researchers can better understand its function and potential implications in disease pathology.With its validation for use in Western blot applications, the Rab1A Polyclonal Antibody enables precise detection and analysis of Rab1A protein levels in different cell types. This makes it a valuable tool for studies in molecular biology, cell biology, and disease mechanisms that involve Rab1A-mediated membrane trafficking pathways.
Product Name:
RAB1A Rabbit Polyclonal Antibody
SKU:
CAB17364
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-205 of human RAB1A (NP_004152.1).
Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, Melanosome, Membrane, cytosol.
Calculated MW:
23kDa
Observed MW:
23kDa
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
5861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB1A antibody (CAB17364) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
