The Rab1A Polyclonal Antibody (CAB14663) is a valuable tool for researchers investigating Rab1A, a key protein involved in intracellular membrane trafficking and vesicular transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blotting applications.Rab1A is a small GTPase that plays a crucial role in maintaining cellular homeostasis by regulating various cellular processes, including protein transport and secretion. Dysregulation of Rab1A has been linked to various diseases, making it a promising target for therapeutic interventions.
The Rab1A Polyclonal Antibody enables researchers to detect and analyze Rab1A protein levels in different cell types, facilitating the study of its function in cellular biology and disease pathogenesis.With its ability to specifically bind to Rab1A, this antibody is a valuable tool for investigations in cell biology, molecular biology, and pharmacology. By gaining insights into the role of Rab1A in cellular pathways, researchers can potentially identify new therapeutic strategies for diseases associated with Rab1A dysfunction.
Product Name:
RAB1A Rabbit Polyclonal Antibody
SKU:
CAB14663
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RAB1A (NP_004152.1).
Cytoplasm, Early endosome, Endoplasmic reticulum, Golgi apparatus, Melanosome, Membrane, cytosol.
Calculated MW:
23kDa
Observed MW:
23kDa
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.
Purification Method:
Affinity purification
Gene ID:
5861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB1A Rabbit pAb (CAB14663) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.