The Rab17 Polyclonal Antibody (CAB7831) is a valuable tool for researchers studying Rab17, a small GTPase involved in regulating membrane trafficking and vesicular transport within cells. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards Rab17 in human samples, making it ideal for use in Western blot applications.Rab17 plays a crucial role in the coordination of intracellular membrane trafficking pathways, including endocytosis and recycling of membrane proteins. Dysregulation of Rab17 has been linked to various diseases such as cancer, neurodegenerative disorders, and metabolic diseases.
By targeting Rab17 with this specific polyclonal antibody, researchers can study its mechanisms of action and potential therapeutic implications in these pathological conditions.With its ability to detect and quantify Rab17 in various cell types and tissues, the Rab17 Polyclonal Antibody (CAB7831) is a valuable tool for investigations in cell biology, cancer research, and drug development. Researchers can utilize this antibody to gain insights into the role of Rab17 in intracellular trafficking and its implications in disease pathology, paving the way for new therapeutic strategies targeting Rab17-mediated pathways.
Product Name:
RAB17 Rabbit Polyclonal Antibody
SKU:
CAB7831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human RAB17 (NP_071894.1).
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).
Purification Method:
Affinity purification
Gene ID:
64284
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB17 antibody (CAB7831) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
