The Rab14 Polyclonal Antibody (CAB12752) is a valuable tool for researchers studying Rab14, a key protein involved in intracellular vesicle trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to Rab14, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology, molecular biology, and membrane trafficking.Rab14 plays a crucial role in regulating vesicle transport, contributing to the proper functioning of organelles and cellular processes. Its involvement in endocytic recycling and exocytic pathways highlights its importance in maintaining cellular homeostasis and communication.
By studying Rab14, researchers can gain insights into cell signaling, membrane dynamics, and disease mechanisms related to vesicle trafficking disruptions.The Rab14 Polyclonal Antibody is a valuable tool for unraveling the functions and mechanisms of Rab14 in cellular processes, offering researchers the opportunity to deepen their understanding of intracellular trafficking and the potential implications for diseases such as neurodegenerative disorders, metabolic diseases, and infectious diseases.
Product Name:
RAB14 Rabbit Polyclonal Antibody
SKU:
CAB12752
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 39-140 of human RAB14 (NP_057406.2).
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).
Purification Method:
Affinity purification
Gene ID:
51552
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Neuro-2a cells, using RAB14 antibody (CAB12752) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
