The Rab12 Polyclonal Antibody (CAB14320) is a valuable tool for researchers studying Rab12, a small GTPase involved in membrane trafficking and autophagy pathways. This antibody is raised in rabbits and is highly specific for Rab12 in human samples, making it suitable for applications such as Western blot and immunofluorescence.Rab12 is known to play important roles in regulating vesicle transport and protein sorting, making it essential for cellular processes such as endocytosis and lysosomal degradation. Dysregulation of Rab12 has been linked to various human diseases, including neurodegenerative disorders and cancer, highlighting the importance of studying its function and regulation.
With its high specificity and sensitivity, the Rab12 Polyclonal Antibody is an essential tool for researchers seeking to unravel the complex roles of Rab12 in cellular physiology and disease pathology. It enables precise detection and analysis of Rab12 protein levels in different cell types, providing valuable insights into its involvement in various biological processes. Discover the potential of Rab12 in your research with the reliable performance of this polyclonal antibody.
Product Name:
RAB12 Rabbit Polyclonal Antibody
SKU:
CAB14320
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RAB12 (NP_001020471.2).
Sequence:
MDPG AALQ RRAG GGGG LGAG SPAL SGGQ GRRR KQPP RPAD FKLQ VIII GSRG VGKT SLME RFTD DTFC EA
Enables GDP binding activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; endosome to lysosome transport; and secretion by cell. Predicted to act upstream of or within cellular response to interferon-gamma. Predicted to be located in lysosome; phagocytic vesicle; and recycling endosome membrane. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
201475
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB12 Rabbit pAb (CAB14320) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
