The Rab11Fip4 Polyclonal Antibody (CAB15914) is specifically designed for research involving Rab11Fip4, a key protein involved in regulating intracellular trafficking and endosomal recycling processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Rab11Fip4 is known for its role in controlling the recycling of endocytic vesicles back to the plasma membrane, as well as its involvement in various cellular processes such as cell division, cell migration, and cytokinesis. Understanding the function of Rab11Fip4 is important in unraveling its contribution to various physiological and pathological conditions, including cancer, neurodegenerative diseases, and infectious diseases.
By using the Rab11Fip4 Polyclonal Antibody, researchers can detect and analyze Rab11Fip4 protein expression in different cell types, providing valuable insights into its role in intracellular trafficking and cellular signaling pathways. This antibody is an essential tool for studies in cell biology, molecular biology, and disease mechanisms, paving the way for potential therapeutic interventions targeting Rab11Fip4-mediated processes.
Product Name:
RAB11FIP4 Rabbit Polyclonal Antibody
SKU:
CAB15914
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 338-637 of human RAB11FIP4 (NP_116321.2).
The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma.
Purification Method:
Affinity purification
Gene ID:
84440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using RAB11FIP4 Rabbit pAb (CAB15914) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 15s.
