The Rab11FIP2 Polyclonal Antibody (PAC02726) is a valuable tool for researchers studying Rab11FIP2, a key protein involved in intracellular trafficking and vesicle transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.Rab11FIP2, a member of the Rab11 family interacting proteins, plays a critical role in regulating the recycling of endosomes and trafficking of membrane proteins. Its function in intracellular transport pathways makes it a vital target for investigation in cell biology and molecular biology research.
By targeting Rab11FIP2, researchers can gain insights into the mechanisms underlying vesicle trafficking and identify potential therapeutic targets for diseases linked to disrupted intracellular transport.This Rab11FIP2 antibody offers researchers a reliable tool for detecting and analyzing Rab11FIP2 protein expression in a variety of cell types, facilitating studies on intracellular trafficking, vesicle recycling, and membrane protein localization. Its specificity and sensitivity make it an essential reagent for studies aiming to unravel the complex roles of Rab11FIP2 in cellular processes.
Antibody Name:
RAB11FIP2 Antibody
Antibody SKU:
PACO02726
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human Rab11-FIP2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11
UniProt Protein Function:
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
