The Rab11Fip1 Polyclonal Antibody (CAB9215) is a valuable tool for research involving Rab11Fip1, a key protein involved in intracellular trafficking and membrane recycling processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Rab11Fip1 protein, this antibody allows for accurate detection and analysis of Rab11Fip1 in various cell types, making it ideal for studies in cell biology, molecular biology, and cancer research.Rab11Fip1 is crucial for the proper functioning of endosomal recycling pathways, which play a critical role in maintaining cellular homeostasis and regulating membrane dynamics.
Dysregulation of Rab11Fip1 has been associated with various diseases, including cancer and neurodegenerative disorders, highlighting its importance as a potential therapeutic target. By studying the activity of Rab11Fip1, researchers can gain valuable insights into cellular processes and disease mechanisms, ultimately paving the way for the development of targeted therapies and treatments.
Product Name:
RAB11FIP1 Rabbit Polyclonal Antibody
SKU:
CAB9215
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-540 of human RAB11FIP1 (NP_079427.4).
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome.
Purification Method:
Affinity purification
Gene ID:
80223
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAB11FIP1 Rabbit pAb (CAB9215) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
