The Rab11b Polyclonal Antibody (CAB15350) is a specialized tool for researchers studying the Rab11b protein, an important regulator of intracellular protein trafficking and membrane recycling processes. Raised in rabbits, this antibody exhibits high reactivity with samples from various species and is validated for use in Western blotting applications.Rab11b is a member of the Rab GTPase family, known for its role in directing vesicular transport and endocytic recycling pathways within cells. Its involvement in cellular processes such as receptor recycling, cytokinesis, and cell signaling makes it a key target for investigation in cell biology and molecular biology studies.
By specifically binding to Rab11b protein, this polyclonal antibody enables precise detection and analysis of Rab11b expression levels in different cell types, providing valuable insights into its functions and regulatory mechanisms. Researchers in fields such as cell biology, biochemistry, and pharmacology can utilize this antibody to further elucidate the role of Rab11b in cellular physiology and disease pathology.
Product Name:
RAB11B Rabbit Polyclonal Antibody
SKU:
CAB15350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB11B (NP_004209.2).
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).
Purification Method:
Affinity purification
Gene ID:
9230
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using RAB11B antibody (CAB15350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
