The Rab11a Polyclonal Antibody (CAB1167) is a valuable tool for researchers studying Rab11a, a member of the Rab GTPase family known for its role in regulating intracellular membrane trafficking. This antibody, generated in rabbits, is highly specific for detecting Rab11a in various cell types and tissues, making it ideal for use in immunofluorescence and immunohistochemistry applications.Rab11a is involved in numerous cellular processes, including endocytic recycling, cytokinesis, and phagocytosis. Dysregulation of Rab11a has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.
Therefore, understanding the function and regulation of Rab11a is essential for developing targeted therapies and understanding disease pathology.The Rab11a Polyclonal Antibody (CAB1167) provides researchers with a reliable tool for studying Rab11a expression and localization in cellular systems, paving the way for advancements in cell biology, molecular biology, and disease research. By using this antibody, researchers can further elucidate the role of Rab11a in health and disease, leading to potential therapeutic interventions and diagnostic applications.
Product Name:
RAB11A Rabbit Polyclonal Antibody
SKU:
CAB1167
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB11A (NP_004654.1).
The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8766
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RAB11A antibody (CAB1167) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
