The Rab10 Polyclonal Antibody (CAB4459) is a valuable tool for researchers studying Rab10, a small GTPase involved in intracellular membrane trafficking and regulation of cellular processes. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples and has been validated for Western blot applications. Rab10 is known for its role in regulating vesicle trafficking and protein transport in cells, making it a key player in various cellular functions. By targeting the Rab10 protein, this antibody allows for the detection and analysis of Rab10 in different cell types, providing valuable insights for studies in cell biology and molecular signaling pathways.
Research on Rab10 has implications in understanding diseases such as neurodegenerative disorders, metabolic disorders, and cancer, where dysregulation of intracellular trafficking pathways can contribute to disease progression. By utilizing the Rab10 Polyclonal Antibody, researchers can further explore the functions and mechanisms of Rab10 in these pathological conditions, opening up potential therapeutic targets for future treatment strategies.
Product Name:
RAB10 Rabbit Polyclonal Antibody
SKU:
CAB4459
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 98-198 of human RAB10 (NP_057215.3).
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).
Purification Method:
Affinity purification
Gene ID:
10890
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of NIH/3T3, using RAB10 Rabbit pAb (CAB4459) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
