The R3HCC1L Polyclonal Antibody (PAC02336) is a powerful tool for research involving the R3HCC1L protein, a key regulator of cellular processes. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the R3HCC1L protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in molecular biology and cancer research.
R3HCC1L is a multifunctional protein involved in regulating gene expression, RNA processing, and cell proliferation. Its intricate role in cellular pathways makes it a pivotal target for investigations into cancer development, genetic disorders, and other diseases. Understanding the functions of R3HCC1L is crucial for advancing our knowledge of cellular biology and identifying potential therapeutic targets for various conditions.
Synthesized peptide derived from internal of human GIDRP88.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from Jurkat cells and COS cells, using GIDRP88 antibody.
Immunohistochemistry analysis of paraffin-embedded human tesophagusis tissue using GIDRP88 antibody.
Background:
3 isoforms of the human protein are produced by alternative splicing.
Synonyms:
GIDRP; GIDRP86; growth inhibition and differentiation-related 88; mitochondrial space protein 32.1; PSORT
UniProt Protein Function:
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
