RSPO1 Rabbit Polyclonal Antibody (CAB8289)
- SKU:
- CAB8289
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | RSPO1 Rabbit Polyclonal Antibody |
SKU: | CAB8289 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-210 of human RSPO1 (NP_001033722.1). |
Sequence: | DMNK CIKC KIEH CEAC FSHN FCTK CKEG LYLH KGRC YPAC PEGS SAAN GTME CSSP AQCE MSEW SPWG PCSK KQQL CGFR RGSE ERTR RVLH APVG DHAA CSDT KETR RCTV RRVP CPEG Q |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | RSPO; CRISTIN3; RSPO1 |
Positive Sample: | SKOV3,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 29kDa |
Observed MW: | 29kDa |
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 284654 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |