QPRT Rabbit Polyclonal Antibody (CAB14349)
- SKU:
- CAB14349
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | QPRT Rabbit Polyclonal Antibody |
SKU: | CAB14349 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2). |
Sequence: | MDAE GLAL LLPP VTLA ALVD SWLR EDCP GLNY AALV SGAG PSQA ALWA KSPG VLAG QPFF DAIF TQLN CQVS WFLP EGSK LVPV ARVA EVRG PAHC LLLG ERVA LNTL ARCS GIAS AAAA AVEA ARGA GWTG HVAG TRKT TPGF RLVE KYGL LVGG AASH RYDL GGLV MVKD NHVV AAGG VEKA VRAA RQAA DFAL KVEV ECSS LQEA VQAA EAGA DLVL LDNF KPEE LHPT ATVL KAQF PSVA VEAS GGIT LDNL PQFC GPHI DVIS MGML TQAA PALD FSLK LFAK EVAP VPKI H |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | QPRTase; HEL-S-90n; QPRT |
Positive Sample: | Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 31kDa |
Observed MW: | 31kDa |
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 23475 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |