The QPCT Polyclonal Antibody (CAB6711) is a valuable tool for research involving QPCT, a protein involved in the regulation of peptide hormones. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to QPCT, this antibody allows for the detection and analysis of QPCT protein levels in a variety of cell types, making it ideal for studies in endocrinology and peptide hormone regulation.QPCT, also known as glutaminyl-peptide cyclotransferase, plays a crucial role in the processing and regulation of peptide hormones, including the conversion of glutaminyl peptides into pyroglutamyl peptides.
Dysfunction of QPCT has been implicated in various diseases, such as Alzheimer's disease and diabetes, highlighting the importance of studying this protein in both normal and pathological conditions.By using the QPCT Polyclonal Antibody (CAB6711), researchers can gain valuable insights into the role of QPCT in peptide hormone regulation and its potential implications for disease development and treatment. This antibody provides a reliable tool for investigating the molecular mechanisms underlying peptide hormone processing, offering new opportunities for therapeutic interventions in related disorders.
Product Name:
QPCT Rabbit Polyclonal Antibody
SKU:
CAB6711
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-361 of human QPCT (NP_036545.1).
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.
Purification Method:
Affinity purification
Gene ID:
25797
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using QPCT Rabbit pAb (CAB6711) at 1:2500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
