QDPR Rabbit Polyclonal Antibody (CAB5733)
- SKU:
- CAB5733
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | QDPR Rabbit Polyclonal Antibody |
SKU: | CAB5733 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human QDPR (NP_000311.2). |
Sequence: | MAAA AAAG EARR VLVY GGRG ALGS RCVQ AFRA RNWW VASV DVVE NEEA SASI IVKM TDSF TEQA DQVT AEVG KLLG EEKV DAIL CVAG GWAG GNAK SKSL FKNC DLMW KQSI WTST ISSH LATK HLKE GGLL TLAG AKAA LDGT PGMI GYGM AKGA VHQL CQSL AGKN SGMP PGAA AIAV LPVT LDTP MNRK SMPE ADFS SWTP LEFL VETF HDWI TGKN RPSS GSLI QVVT TEGR TELT PAYF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DHPR; PKU2; HDHPR; SDR33C1; QDPR |
Positive Sample: | Mouse liver,Mouse kidney,Mouse brain,Rat liver,HL-60,BT-474,SW620 |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, extracellular exosome |
Calculated MW: | 26kDa |
Observed MW: | 26kDa |
This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Purification Method: | Affinity purification |
Gene ID: | 5860 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |