The PYCR2 Polyclonal Antibody (CAB15155) is a powerful tool for researchers studying PYCR2, a key enzyme involved in proline biosynthesis essential for cell proliferation and collagen synthesis. This antibody, produced using rabbits as hosts, exhibits high reactivity with human samples and has been validated for Western blot applications. By targeting the PYCR2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in the fields of biochemistry and cancer biology.
PYCR2 is crucial for maintaining cellular functions and is implicated in various diseases such as cancer, metabolic disorders, and connective tissue disorders. Understanding the role of PYCR2 in these pathological conditions can provide insights into novel therapeutic strategies targeting proline metabolism. The PYCR2 Polyclonal Antibody is a valuable tool for researchers aiming to unravel the complex mechanisms involving PYCR2 and its potential as a therapeutic target in disease management.
Product Name:
PYCR2 Rabbit Polyclonal Antibody
SKU:
CAB15155
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 271-320 of human PYCR2 (NP_037460.2).
This gene belongs to the pyrroline-5-carboxylate reductase family. The encoded mitochondrial protein catalyzes the conversion of pyrroline-5-carboxylate to proline, which is the last step in proline biosynthesis. Alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
29920
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PYCR2 Rabbit pAb (CAB15155) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
