The PXN Polyclonal Antibody (CAB18181) is a valuable tool for research involving PXN, a key protein involved in cell adhesion and migration. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it ideal for Western blot applications. By binding to PXN, the antibody enables accurate detection and analysis of this important protein in various cell types.PXN, also known as paxillin, plays a crucial role in cell signaling pathways that control cytoskeletal dynamics and cell movement. Its involvement in cell adhesion and migration processes makes it a promising target for studying cancer metastasis, wound healing, and other cellular processes.
Understanding the function of PXN is essential for exploring its potential role in disease development and progression.Researchers in the fields of cell biology, cancer research, and developmental biology will benefit from using the PXN Polyclonal Antibody in their studies. Its specificity and reliability make it a valuable tool for investigating the role of PXN in various physiological and pathological contexts.
Product Name:
Paxillin Rabbit Polyclonal Antibody
SKU:
CAB18181
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Paxillin (NP_002850.2).
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
Purification Method:
Affinity purification
Gene ID:
5829
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells, using Paxillin Rabbit pAb (CAB18181) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
