The PXDN Polyclonal Antibody (CAB17929) is a valuable tool for researchers studying PXDN, a protein involved in the regulation of cell adhesion and migration. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PXDN protein, the antibody allows for the detection and analysis of PXDN in a variety of cell types, making it well-suited for studies in cell biology and cancer research.PXDN, also known as peroxidasin, plays a crucial role in extracellular matrix remodeling and cell migration, making it a key player in processes like wound healing and tissue development.
Dysregulation of PXDN has been linked to various diseases, including cancer and fibrosis, highlighting its importance as a therapeutic target. Investigating the function of PXDN is essential for understanding its role in health and disease, and for developing targeted therapies that may benefit patients in need.
Product Name:
PXDN Rabbit Polyclonal Antibody
SKU:
CAB17929
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1320-1479 of human PXDN (NP_036425.1).
This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.
Purification Method:
Affinity purification
Gene ID:
7837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse lung, using PXDN antibody (CAB17929) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
