The PWP1 Monoclonal Antibody is a cutting-edge tool for researchers studying PWP1, a protein involved in gene regulation and chromatin remodeling. This antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity for detecting PWP1 in various biological samples, including human tissues. It has been rigorously validated for use in techniques such as immunofluorescence, immunohistochemistry, and flow cytometry.PWP1, also known as regulatory subunit of protein phosphatase 1, is essential for the maintenance of genomic stability and the control of gene expression.
Dysregulation of PWP1 has been implicated in a variety of diseases, including cancer and developmental disorders. By targeting PWP1 with this monoclonal antibody, researchers can gain valuable insights into its function and potential therapeutic applications. Whether investigating the role of PWP1 in cell cycle progression or uncovering its involvement in disease pathways, this antibody is a versatile tool for advancing biomedical research.
Product Name:
PWP1 Monoclonal Antibody
SKU:
CAB21143
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-501 of human PWP1 (NP_008993.1).
The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
11137
Clone Number:
ARC3017
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PWP1 Rabbit mAb (CAB21143) at1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
