PVRL4 Rabbit Polyclonal Antibody (CAB16149)
- SKU:
- CAB16149
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PVRL4 Rabbit Polyclonal Antibody |
SKU: | CAB16149 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-146 of human PVRL4 (NP_112178.2). |
Sequence: | GELE TSDV VTVV LGQD AKLP CFYR GDSG EQVG QVAW ARVD AGEG AQEL ALLH SKYG LHVS PAYE GRVE QPPP PRNP LDGS VLLR NAVQ ADEG EYEC RVST FPAG SFQA RLRL RVL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | LNIR; PRR4; EDSS1; PVRL4; nectin-4 |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Secreted, Single-pass type I membrane protein, adherens junction |
Calculated MW: | 55kDa |
Observed MW: | 62kDa/75kDa |
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 81607 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |