The PVRL3 Polyclonal Antibody (CAB4597) is a valuable tool for researchers studying the PVRL3 protein, a member of the poliovirus receptor-like protein family involved in cell adhesion and immune response modulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PVRL3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and cancer research.
PVRL3 is known for its role in mediating cell-cell adhesion and interactions within the immune system. It has been implicated in various diseases, including cancer and inflammatory conditions, highlighting its importance in immune function and disease progression. Researchers can use this antibody to further investigate the role of PVRL3 in these contexts and potentially develop targeted therapies for related disorders.
Product Name:
PVRL3 Polyclonal Antibody
SKU:
CAB4597
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 127-366 of human PVRL3 (NP_001230215.1).
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
25945
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse testis, using PVRL3 Rabbit pAb (CAB4597) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 45s.
