The PVDA Antibody (PAC050646) is a polyclonal antibody specifically designed for research involving the PVDA protein. PVDA, a cell surface molecule, is known for its role in immune regulation, particularly in inhibiting immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding to the PVDA protein, this antibody enables the detection and analysis of PVDA in various cell types. It is well-suited for studies in immunology and cancer research, providing researchers with a valuable tool to investigate the function and significance of PVDA in immune response modulation.
PVDA has been identified as an important immune inhibitory receptor, playing a crucial role in immune homeostasis by regulating inflammation and inhibiting allergic reactions. Research into PVDA is essential for gaining insights into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By understanding the activity of PVDA, researchers can develop new therapies that target or modulate immune function in the context of these diseases.
Antibody Name:
pvdA Antibody (PACO50646)
Antibody SKU:
PACO50646
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Pseudomonas aeruginosa
Immunogen:
Recombinant Pseudomonas aeruginosa L-ornithine N(5)-monooxygenase protein (1-443AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: pvdA antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65 kDa. Observed band size: 65 kDa..
Background:
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr-L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr-L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
