The PVALB Polyclonal Antibody (CAB13538) is a valuable tool for researchers studying the protein PVALB, which plays a crucial role in calcium signaling and muscle contraction. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting PVALB in human samples, making it ideal for use in Western blot applications. By targeting the PVALB protein, researchers can gain insights into its function in muscle physiology and potentially uncover new therapeutic targets for muscle-related disorders.PVALB, also known as parvalbumin, is a calcium-binding protein found in fast-twitch muscle fibers and certain neurons. Its involvement in regulating intracellular calcium levels positions it as a key player in muscle contraction and relaxation mechanisms.
Furthermore, dysregulation of PVALB has been linked to muscle disorders such as myopathies and muscle spasms, highlighting its clinical relevance.By utilizing the PVALB Polyclonal Antibody in their research, scientists can deepen their understanding of PVALB's role in muscle function and pathology. This antibody provides a valuable tool for investigating the molecular mechanisms underlying muscle disorders and may pave the way for the development of novel therapeutic strategies targeting PVALB in the future.
Product Name:
Parvalbumin (PVALB) Rabbit Polyclonal Antibody
SKU:
CAB13538
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human Parvalbumin (Parvalbumin (PVALB)) (NP_002845.1).
The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5816
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Parvalbumin (PVALB) Rabbit pAb (CAB13538) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
