The PUS7 Polyclonal Antibody (CAB17710) is a valuable tool for researchers studying PUS7, a protein involved in RNA modification and regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the PUS7 protein, this antibody allows for the detection and analysis of PUS7 in various cell types, making it ideal for studies in molecular biology and RNA biology.PUS7 plays a crucial role in maintaining RNA integrity and function by catalyzing the formation of pseudouridine, a modified nucleoside essential for proper RNA folding and stability.
Dysregulation of PUS7 has been linked to various diseases, including cancer and neurological disorders, highlighting the importance of understanding its function. By studying the activity of PUS7, researchers can gain insights into RNA modification pathways and potentially identify novel therapeutic targets for disease intervention.
Product Name:
PUS7 Rabbit Polyclonal Antibody
SKU:
CAB17710
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 352-661 of human PUS7 (NP_061915.2).
Enables enzyme binding activity and pseudouridine synthase activity. Involved in several processes, including pseudouridine synthesis; regulation of hematopoietic stem cell differentiation; and regulation of mesoderm development. Located in nucleus.
Purification Method:
Affinity purification
Gene ID:
54517
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PUS7 Rabbit pAb (CAB17710) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
