The PUS3 Polyclonal Antibody (PAC011613) is a valuable tool for researchers studying PUS3, a protein involved in RNA modification processes. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PUS3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for research in molecular biology and genetics.PUS3 is an essential enzyme involved in post-transcriptional modifications of RNA, specifically in the process of pseudouridylation. As pseudouridylation plays a crucial role in RNA stability and function, PUS3 is implicated in various biological processes, including gene expression regulation and RNA metabolism.
Research into PUS3 can provide insights into RNA modification pathways and their impact on cellular functions.The PUS3 Polyclonal Antibody is a valuable tool for researchers investigating RNA modification mechanisms and their roles in gene regulation and cellular physiology. By studying PUS3, researchers can gain a better understanding of the intricate processes involved in RNA modification and their implications for various biological processes.
PUS3: Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs. Belongs to the tRNA pseudouridine synthase TruA family.Protein type: EC 5.4.99.45; Nuclear receptor co-regulator; Isomerase; RNA processingChromosomal Location of Human Ortholog: 11q24.2
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
