PUS10 Rabbit Polyclonal Antibody (CAB15962)
- SKU:
- CAB15962
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PUS10 Rabbit Polyclonal Antibody |
SKU: | CAB15962 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-529 of human PUS10 (NP_653310.2). |
Sequence: | VAGR YNKY SRNL PQTP WIID GERK LESS VEEL ISDH LLAV FKAE SFNF SSSG REDV DVRT LGNG RPFA IELV NPHR VHFT SQEI KELQ QKIN NSSN KIQV RDLQ LVTR EAIG HMKE GEEE KTKT YSAL IWTN KAIQ KKDI EFLN DIKD LKID QKTP LRVL HRRP LAVR ARVI HFME TQYV DEHH FRLH LKTQ AGTY IKEF VHGD FGRT KPNI GSLM NVTA DILE LDVE SVDV DWPP ALDD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DOBI; Hup10; CCDC139; PUS10 |
Positive Sample: | Mouse thymus,Mouse spleen,Mouse testis,Rat thymus |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, mitochondrion, nucleus |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).
Purification Method: | Affinity purification |
Gene ID: | 150962 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |