The Purified Mouse TCR Monoclonal Antibody (H57-597) is a specialized tool designed for the study of T cell receptor (TCR) molecules in mice. This monoclonal antibody, known as HB218 (AGEL1536), has been meticulously developed to specifically target and bind to mouse TCR, enabling precise detection and analysis in various experimental settings.TCR molecules are essential components of the immune system, playing a crucial role in T cell recognition and response to antigens. The H57-597 monoclonal antibody is an invaluable resource for researchers investigating T cell function, activation, and signaling pathways in mouse models.
Its high specificity and sensitivity make it a reliable reagent for applications such as flow cytometry, immunoprecipitation, and immunohistochemistry.By utilizing the Purified Mouse TCR Monoclonal Antibody (H57-597), researchers can gain valuable insights into the behavior and function of T cells in mouse immune responses. This antibody opens up new possibilities for understanding the intricate mechanisms of immune regulation and the development of novel approaches for immunotherapy and disease treatment in preclinical research settings.
Purified Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.