The Purified Anti-Mouse IL-2 Antibody (JES6-5H4) from Assay Genie (www.assaygenie.com/purified-anti-mouse-il-2-antibody-jes6-5h4/) is an essential tool for researchers working with mouse models studying interleukin-2 (IL-2), a key cytokine involved in immune responses and regulatory T cell function.This antibody, produced through a purification process, is highly specific to the IL-2 protein in mice and is validated for use in various immunological applications such as flow cytometry, immunoprecipitation, and immunohistochemistry. By targeting IL-2, researchers can gain insights into the regulation of T cell activation, differentiation, and proliferation, as well as the development and function of regulatory T cells.
IL-2 is a critical signaling molecule that influences the balance between effector and regulatory immune responses, making it a crucial target for studies in immunology, autoimmunity, transplant rejection, and cancer immunotherapy research. The Purified Anti-Mouse IL-2 Antibody (JES6-5H4) offers high specificity and sensitivity, making it an invaluable tool for investigating the role of IL-2 in immune homeostasis and disease pathogenesis in mouse models.
Product Title:
Purified Anti-Mouse IL-2 Antibody [JES6-5H4]
SKU:
AGEL2376
Size:
25µg, 100µg
Clone No:
JES6-5H4
Synonyms:
Interleukin-2;IL-2;T-cell growth factor;TCGF;IL2;
Host Species:
Rat
Reactivity:
Mouse
Application:
ICFCM;ELISA
Isotype:
Rat IgG2b, κ
Isotype Control:
Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 0.5-2.0 µg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-2 recombinant protein ranging from 250 to 2 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.