The Purified Anti-Mouse H-2 Antibody (M1/42) offered by AssayGenie is a powerful tool for researchers studying the immune responses of mice. This antibody, specifically targeting the H-2 antigen, is produced through meticulous purification processes to ensure high specificity and sensitivity in a variety of experimental applications.The M1/42 antibody is well-suited for use in immunology studies, particularly for investigating the role of H-2 antigens in immune recognition and responses. Its reactivity with mouse samples allows for accurate detection and quantification of H-2 antigens in different cell types and tissues. Researchers can rely on the reliability and consistency of this antibody for Western blot, immunohistochemistry, and flow cytometry experiments.
The H-2 antigen is a key player in the immune system of mice, influencing immune surveillance, antigen presentation, and immune tolerance. By utilizing the Purified Anti-Mouse H-2 Antibody (M1/42), researchers can delve deeper into the mechanisms underlying immune responses in mouse models of disease, paving the way for a better understanding of immune-related conditions such as autoimmune disorders, infections, and cancer.Enhance your research capabilities with the Purified Anti-Mouse H-2 Antibody (M1/42) from AssayGenie and unlock new insights into the intricate interplay of immune components in mouse models.
Product Title:
Purified Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2408
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Purified Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.