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Purified Anti-Mouse CD38 Antibody [NIMR5] (AGEL2362)

SKU:
AGEL2362
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
NIMR5
Conjugation:
Unconjugated
€139 - €199
Frequently bought together:

Description

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Purified Anti-Mouse CD38 Antibody [NIMR5]

The NimR5 Purified Anti-Mouse CD38 Antibody offered by AssayGenie (www.assaygenie.com/purified-anti-mouse-cd38-antibody-nimr5/) is a premium research tool designed for scientists studying CD38, a cell surface glycoprotein involved in various physiological processes, including immune response modulation and cell signaling pathways. This antibody is specifically tailored for detecting and analyzing CD38 expression in mouse samples, making it an essential component for immunology and cancer research studies.Raised against mouse CD38, the NimR5 Antibody showcases high specificity and sensitivity in detecting the target protein, ensuring accurate and reliable results in experimental settings. Validated for use in applications such as immunohistochemistry, flow cytometry, and Western blotting, researchers can confidently utilize this antibody to explore the expression and function of CD38 in different cell types and tissues.

CD38 is a multifunctional protein implicated in immune regulation, calcium signaling, and cell adhesion, making it a key molecule of interest in various research fields, including immunology and oncology. By targeting CD38 with the NimR5 Antibody, scientists can gain valuable insights into the role of this protein in disease processes such as cancer progression, autoimmune disorders, and inflammatory conditions, paving the way for the development of novel therapeutic strategies targeting CD38-mediated pathways.In summary, the NimR5 Purified Anti-Mouse CD38 Antibody from AssayGenie is a reliable and efficient tool for investigating the biological functions of CD38 in mouse models, offering researchers a powerful means to deepen their understanding of immune regulation, cell signaling, and disease mechanisms.

Product Title:Purified Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2362
Size:25µg, 100µg
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P56528
Gene ID:12494
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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