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Purified Anti-Mouse CD366/Tim-3 Antibody [RMT3-23] (AGEL2361)

SKU:
AGEL2361
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
RMT3-23
Conjugation:
Unconjugated
$167 - $239
Frequently bought together:

Description

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Purified Anti-Mouse CD366/Tim-3 Antibody [RMT3-23]

The Purified Anti-Mouse CD366 (Tim-3) Antibody (RMT3-23) is a cutting-edge tool designed for researchers studying immune regulation and immune responses in mice. The antibody, meticulously produced and purified, specifically targets the CD366 protein, also known as Tim-3, a key immune checkpoint receptor involved in T cell exhaustion and regulation. This high-quality antibody, optimized for use in various applications, ensures precise detection and analysis of CD366/Tim-3 expression in mouse samples. It offers researchers a reliable means to investigate the role of Tim-3 in immune responses, particularly in the context of cancer, infectious diseases, and autoimmune disorders.

With its exceptional specificity and reactivity, the Purified Anti-Mouse CD366 (Tim-3) Antibody (RMT3-23) is an indispensable tool for immunologists and researchers delving into the intricate mechanisms of immune regulation in mouse models. Unlock new insights into immune checkpoints and discover novel therapeutic targets with this advanced antibody.

Product Title:Purified Anti-Mouse CD366/Tim-3 Antibody [RMT3-23]
SKU:AGEL2361
Size:25µg, 100µg
Clone No:RMT3-23
Synonyms:TIM3; TIMD3;HAVcr-2;TIMD-3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q8VIM0
Gene ID:84868
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

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