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Purified Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL3504)

SKU:
AGEL3504
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
A7R34
Conjugation:
Unconjugated
€139 - €199
Frequently bought together:

Description

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Purified Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Purified Anti-Mouse CD127 (IL-7RA) Antibody (A7R34) is a cutting-edge tool designed for precise and reliable research applications involving the CD127 (IL-7RA) protein. This antibody, specifically produced for use in mouse samples, is derived from high-quality sources and extensively validated for various experimental methods, including flow cytometry and immunohistochemistry.CD127, also known as interleukin-7 receptor alpha, plays a pivotal role in immune cell development and function, particularly in the regulation of T cell survival and homeostasis. It is a key player in immune system modulation, making it a crucial target for studies in immunology, cancer research, and autoimmune diseases.

The Purified Anti-Mouse CD127 (IL-7RA) Antibody (A7R34) enables precise and specific detection of CD127, facilitating in-depth analysis of its expression and function in diverse cell populations.By utilizing this advanced antibody, researchers can delve deeper into the intricate mechanisms governed by CD127 and gain valuable insights into its impact on immune responses and disease processes. With its exceptional quality and specificity, the Purified Anti-Mouse CD127 (IL-7RA) Antibody (A7R34) is an indispensable tool for unraveling the complexities of immune regulation and paving the way for innovative therapeutic interventions.

Product Title:Purified Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL3504
Size:25µg, 100µg
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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