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Purified Anti-Human CD8a Antibody [HIT8a] (AGEL3511)

SKU:
AGEL3511
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
HIT8a
Conjugation:
Unconjugated
€129 - €199
Frequently bought together:

Description

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Purified Anti-Human CD8a Antibody [HIT8a]

The HIT8a Purified Anti-Human CD8a Antibody is a crucial tool for researchers studying the CD8a protein, a key cell surface marker involved in immune responses and cell-mediated immunity. This monoclonal antibody, generated specifically for human samples, is extensively validated for various applications, including flow cytometry, immunohistochemistry, and immunoprecipitation.CD8a is a critical component of cytotoxic T cells and is essential for recognizing and targeting infected or abnormal cells in the body. By specifically binding to CD8a, this antibody allows for the precise identification and analysis of CD8a-expressing cells in different tissues and experimental setups.

This makes it an invaluable resource for investigations in immunology, infectious diseases, and cancer research.The ability to accurately detect and quantify CD8a expression levels can provide insights into immune responses, disease progression, and therapeutic efficacy. Researchers can leverage the HIT8a Purified Anti-Human CD8a Antibody to delve deeper into the complex interactions of the immune system and explore potential targets for immunotherapy and personalized medicine.For high-quality, reliable results in CD8a-related experiments, trust the HIT8a Purified Anti-Human CD8a Antibody from AssayGenie.

Product Title:Purified Anti-Human CD8a Antibody [HIT8a]
SKU:AGEL3511
Size:25µg, 100µg
Clone No:HIT8a
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T8;Leu2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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