The Anti-Human CD5 Antibody (UCHT2) offered by Assay Genie is a premium product designed for researchers studying CD5, a surface marker on T cells and B cells that plays a key role in immune responses. This purified antibody is sourced from mouse hybridoma cells and exhibits high specificity and sensitivity when used in various immunological assays.CD5, a crucial regulator of immune tolerance and activation, is involved in signaling pathways that control lymphocyte development and function. The UCHT2 antibody recognizes and binds specifically to CD5 molecules, facilitating the detection and analysis of CD5 expression in human samples. This makes it an essential tool for investigations into autoimmune diseases, immune system dysregulation, and lymphoproliferative disorders where CD5 expression is implicated.
Researchers can trust the Assay Genie Anti-Human CD5 Antibody (UCHT2) for its reliable performance in techniques such as flow cytometry, immunohistochemistry, and immunoprecipitation. By targeting CD5, this antibody supports a better understanding of immune cell interactions and provides valuable insights into the mechanisms underlying immune-related pathologies and therapeutic interventions. Enhance your research with the precision and quality offered by this specialized antibody from Assay Genie.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.