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Purified Anti-Human CD45RA Antibody [HI100] (AGEL3505)

SKU:
AGEL3505
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2b, k
Clone:
HI100
Conjugation:
Unconjugated
$167 - $275

Description

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Purified Anti-Human CD45RA Antibody [HI100]

The Purified Anti-Human CD45RA Antibody (HI100) offered by Assay Genie is a vital tool for researchers delving into immune cell analysis and characterization. As a monoclonal antibody specific to the CD45RA antigen, this antibody is meticulously purified and validated for its exceptional specificity and sensitivity in various immunological applications.CD45RA, a cell surface marker, is predominantly expressed on naive or resting T cells and a subset of B cells, acting as a key player in immune cell differentiation and activation processes. The HI100 antibody binds specifically to the CD45RA antigen, enabling precise detection and isolation of CD45RA-expressing cells in human samples. This facilitates detailed investigations into immune cell subpopulations, immune responses, and disease mechanisms.

By utilizing the Purified Anti-Human CD45RA Antibody (HI100) in flow cytometry, immunohistochemistry, or immunoprecipitation assays, researchers can uncover valuable insights into immune cell subsets, immune system dynamics, and disease pathology. With its reliability and accuracy, this antibody is an indispensable resource for studies in immunology, oncology, and autoimmune diseases, contributing to advancements in therapeutic strategies and disease management.Assay Genie's Purified Anti-Human CD45RA Antibody (HI100) is a crucial component for researchers seeking to unravel the complexities of the immune system and its role in health and disease. Trust in the exceptional quality and performance of this antibody to drive your research forward and unlock new discoveries in the field of immunology.

Product Title:Purified Anti-Human CD45RA Antibody [HI100]
SKU:AGEL3505
Size:25µg, 100µg
Clone No:HI100
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:Purified Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

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