The HERMES-1 Purified Anti-Human CD44 Antibody offered by Assay Genie is a highly specific research tool designed for the study of the CD44 protein, a cell surface glycoprotein known for its involvement in cell adhesion, migration, and signaling processes. This antibody, generated using advanced purification techniques, is raised against human samples and is suitable for various experimental applications.CD44, a multifunctional cell surface receptor, plays a pivotal role in various physiological and pathological processes, including inflammation, tissue repair, and cancer progression.
By targeting the CD44 protein specifically, researchers can gain valuable insights into its functions within different cell types and its implications in disease mechanisms.The HERMES-1 Purified Anti-Human CD44 Antibody is a reliable tool for detecting and analyzing CD44 expression in both normal and diseased tissues, providing researchers with a deeper understanding of its role in cellular interactions and disease progression. With its high specificity and sensitivity, this antibody is an essential asset for studies focused on immunology, cancer biology, and regenerative medicine.
Product Title:
Purified Anti-Human CD44 Antibody [Hermes-1]
SKU:
AGEL2405
Size:
25µg, 100µg
Clone No:
Hermes-1
Synonyms:
LHR;PGP-I;CDw44;Epican;HUTCH-I;
Host Species:
Rat
Reactivity:
Human
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Purified Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.