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Purified Anti-Human CD40 Antibody [G28.5] (AGEL2402)

SKU:
AGEL2402
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
G28.5
Conjugation:
Unconjugated
€129 - €199
Frequently bought together:

Description

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Purified Anti-Human CD40 Antibody [G28.5]

The Purified Anti-Human CD40 Antibody (G28-5) offered by Assay Genie is a high-quality research tool designed for the study of CD40, a cell surface protein with key roles in immune response modulation. This antibody is specifically designed to target human CD40 and is purified for optimal performance in various research applications. CD40 is a critical regulator of immune responses, mediating interactions between immune cells and playing a crucial role in the activation and differentiation of B cells. The Purified Anti-Human CD40 Antibody (G28-5) provides researchers with a reliable tool to study the functions of CD40 in immunology, cancer research, and other related fields. With its high specificity, reactivity, and validated performance in applications such as Western blotting, this antibody enables precise detection and analysis of CD40 protein expression in a wide range of cell types.

By utilizing this antibody, researchers can gain valuable insights into the mechanisms underlying immune activation, inflammation, and disease processes associated with CD40 dysregulation.For cutting-edge research into immune system function, cancer immunotherapy, and inflammatory disorders, the Purified Anti-Human CD40 Antibody (G28-5) from Assay Genie is an indispensable tool that facilitates in-depth exploration of CD40-mediated pathways and opens new avenues for therapeutic development.

Product Title:Purified Anti-Human CD40 Antibody [G28.5]
SKU:AGEL2402
Size:25µg, 100µg
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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