The Purified Anti-Human CD38 Antibody (HIT2) offered by AssayGenie is a high-quality, specific tool for research targeting the CD38 protein, a key cell surface molecule involved in various immune processes. Produced using advanced purification techniques, this antibody is optimized for use in a variety of applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD38 is a multifunctional protein that plays a critical role in immune regulation, cell signaling, and inflammation. Its expression is particularly important in immune cells and has been implicated in conditions such as cancer, autoimmune diseases, and infectious disorders. The Anti-Human CD38 Antibody (HIT2) enables precise detection and analysis of CD38 levels in human samples, facilitating in-depth studies into the role of this protein in immunological processes.
Ideal for immunology and cancer research studies, this highly specific antibody binds to the CD38 antigen with high affinity, ensuring accurate and reliable results. By investigating the expression and function of CD38, researchers can gain valuable insights into the mechanisms underlying immune dysregulation and explore potential therapeutic targets for various diseases.Thus, the AssayGenie Purified Anti-Human CD38 Antibody (HIT2) serves as a valuable tool for scientists and researchers looking to elucidate the complex functions of CD38 and its implications in health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.