The purified anti-human CD3 Antibody (UCHT1) offered by AssayGenie is a cutting-edge tool for researchers studying immune responses and T-cell activation. This high-quality antibody specifically targets the CD3 antigen, a key component of the T-cell receptor complex essential for T-cell signaling and activation.Derived from a hybridoma culture, this monoclonal antibody demonstrates exceptional specificity and sensitivity in detecting the CD3 antigen in human samples. It is validated for a variety of applications, including flow cytometry, immunohistochemistry, and immunoprecipitation.The CD3 antigen is pivotal in orchestrating T-cell responses to pathogens and other challenges to the immune system.
By utilizing this anti-human CD3 Antibody, researchers can gain insights into T-cell function, immune system dynamics, and the development of immunotherapies for conditions such as autoimmune diseases, viral infections, and cancer.Invest in the purified anti-human CD3 Antibody (UCHT1) from AssayGenie to advance your research in immunology, infectious diseases, and cancer immunotherapy. Unleash the potential of T-cell research with this powerful antibody that promises accurate and reliable results in your experimental studies.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.