The PURG Antibody (PAC061466) is a polyclonal antibody designed for research involving the PURG protein, a key player in gene expression regulation. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in applications such as Western blotting and immunohistochemistry. It binds specifically to the PURG protein, allowing for precise detection and analysis in a variety of cell types.PURG, also known as purine-rich element binding protein G, is involved in the regulation of gene expression at the transcriptional level. Its role in controlling the activity of certain genes makes it a valuable target for research in fields such as molecular biology, genetics, and developmental biology.
Understanding the function of PURG can provide insights into cellular processes and may have implications for various diseases and disorders.Researchers studying gene regulation, RNA processing, and transcriptional control will find the PURG Antibody to be a valuable tool in their experiments. Its high reactivity and specificity make it a reliable choice for investigating the function and localization of the PURG protein in different cellular contexts.
Antibody Name:
PURG Antibody (PACO61466)
Antibody SKU:
PACO61466
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Recombinant Human Purine-rich element-binding protein γ protein (242-345AA)
Western Blot. Positive WB detected in: K562 whole cell lysate, Jurkat whole cell lysate. All lanes: PURG antibody at 5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 40, 37 kDa. Observed band size: 40 kDa.
Synonyms:
Purine-rich element-binding protein gamma, PURG
UniProt Protein Function:
PURG: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]Protein type: Unknown functionChromosomal Location of Human Ortholog: 8p11Cellular Component: nucleusMolecular Function: DNA binding
UniProt Protein Details:
NCBI Summary:
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
